Medical Definition of Thymidine kinase
1.
Of pyrimidine salvage, catalysing phosphorylation of thymine deoxyriboside to form its 5' phosphate, the nucleotide thymidylate. Animal cells lacking this enzyme can be selected by lethal synthesis, for example by resistance to bromodeoxyuridine and can be used as parentals in somatic hybridisation, since they are unable to grow in HAT medium.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
Lexicographical Neighbors of Thymidine Kinase
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