Lexic.us

Definition of Transferrin

1. Noun. A globulin in blood plasma that carries iron.

Definition of Transferrin

1. Noun. (biochemistry) a glycoprotein, a beta globulin, in blood serum that combines with, and transports iron ¹

¹ Source: wiktionary.com

Definition of Transferrin

1. [n -S]

Medical Definition of Transferrin

1. A protein that carries iron in the bloodstream (80 kD) found in mammalian serum, a beta globulin. Binds ferric iron with a Kass of around 21 at pH 7.4, 18.1 at pH 6.6. An important constituent of growth media. Transferrin receptors on the cell surface bind transferrin as part of the transport route of iron into cells. The percentage of transferrin that has iron bound to it is increased in situations of iron overdose and in the disease haemochromatosis. Serum transferrin is decreased in cases of protein deficiency. (17 Mar 1998)

Lexicographical Neighbors of Transferrin

Literary usage of Transferrin

Below you will find example usage of this term as found in modern and/or classical literature:

1. Molecular Neurobiology: Proceedings of the 2nd NIMH Conference by Steven Zalcman (1995)
"If synaptophysin expressed as an exogenous protein is targeted to the pathway that recycles transferrin receptors, then the traffic of synaptophysin and ..."

2. Mineral Tolerance of Animals by National Research Council (U. S.) (2005)
"Metabolic Interactions Once absorbed, iron enters the blood where it is taken up by transferrin (Baker and Morgan, 1994). Iron in circulation is primarily ..."

3. Mineral Requirements for Military Personnel: Levels Needed for Cognitive And by Food and Nutrition Board, Committee on Military Nutrition Research, National Academy of Sciences (U.S.) (2006)
"Serum transferrin saturation. transferrin saturation is defined as [serum] iron/TIBC ... transferrin is a metalloprotein with a very high affinity for iron, ..."

4. Assessing Alcohol Problems: A Guide for Clinicians and Researchers by John P. Allen, Megan Columbus (1997)
"The two tests presently in this category are the blood tests carbohydrate deficient transferrin (CDT) and hemoglobin or •whole blood acetaldehyde adducts ..."

5. Toxicological Profile for Aluminum (Update) (2001)
"Once into the blood, aluminum is believed to be present almost exclusively in the plasma where it is bound mainly to transferrin ..."

6. The South Sea Islanders and the Queensland Labour Trade: A Record of Voyages by William T. Wawn (1893)
"However, the frequency of transferrin DI is low in Australia as in Melanesia, ... Whatever the true explanation, the transferrin D^ variant is unique as a ..."

7. Proceedings of the Scientific Workshop on the Health Effects of Electric and by Philip J. Bierbaum (1994)
"The rationale for this study was the association of the transferrin receptor ... The expression of transferrin receptors in cells exposed to the combined ..."

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