Lexic.us

Definition of Trisomy 21

1. Noun. A congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation.

Definition of Trisomy 21

1. Noun. The presence of three copies of the 21st chromosome in the karyotype. ¹

¹ Source: wiktionary.com

Medical Definition of Trisomy 21

1. A congenital condition which is characterised by moderate to severe mental retardation, slanting eyes, a broad short skull, broad hands and short fingers. Other congenital abnormalities include heart defects, oesophageal atresia and an increased incidence of acute lymphocytic leukaemia. All of these findings are secondary to trisomy (an extra chromosome) of the 21st chromosome. Trisomy 21 can be detected in the first few months of pregnancy by amniocentesis. Risk factors include prior Down's child and mothers who become pregnant after age 40. Synonym: Down's syndrome. (27 Sep 1997)

Lexicographical Neighbors of Trisomy 21

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