Medical Definition of Zimmermann reaction
1. A chemical reaction between an alkaline solution of meta-dinitrobenzene and an active methylene group (carbon-16) of 17-ketosteroids; it is the basis of the 17-ketosteroid assay t.; more generally, a reaction between methylene ketones and aromatic polynitro compounds in alkaline solutions. Synonym: Zimmermann test. (05 Mar 2000)
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