Definition of Down syndrome

1. Noun. A congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation.

Definition of Down syndrome

1. Noun. (chiefly US) Condition caused by a chromosomal excess, whereby the patients bear a certain resemblance to the mongoloid Mongoloid race, such as a small head and tilted eyelids. ¹

¹ Source:

Medical Definition of Down syndrome

1. Trisomy 21, mongolism, atlantoaxial subluxation, Wormian bones, absent/small paranasal sinuses, endocardial cushion (AV canal) defects, aberrant right subclavian artery, 2 ossification centres for manubrium (90%), 11 or 13 ribs, duodenal atresia / stenosis, tracheo-oesophageal fistula, Hirschsprung disease (12 Dec 1998)

Down Syndrome Pictures

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Lexicographical Neighbors of Down Syndrome

down in the heel
down in the heels
down in the mouth
down line
down on one's luck
down pat
down pat(p)
down payment
down payments
down promoter mutation
down quark
down quarks
down start
down style
down syndrome
down tack
down the banks
down the drain
down the hatch
down the line
down the road
down the road, not across the street
down the stairs
down the track
down the tube
down the tubes
down time
down to
down to a T

Literary usage of Down syndrome

Below you will find example usage of this term as found in modern and/or classical literature:

1. Healthy People 2000: National Health Promotion & Disease Prevention by DIANE Publishing Company (2004)
"For example, the proportion of children with Down syndrome with IQs greater than 50 has increased in recent years presumably because of family-centered ..."

2. Guide To Clinical Preventive Services by U. S. Preventive Services Task Force (1989)
"Maternal serum alpha- fetoprotein measurement: a screening test for Down syndrome. Lancet 1984; 1:926-9. 17. Pueschel SM. ..."

3. Health Status of Minorities & Low Income Groups by DIANE Publishing Company, Dept. of Health and Human Services, United States (1991)
"Asians have an increased risk for anencephaly (a 47 percent rate difference) and Down syndrome (33 percent) and other autosomal abnormalities excluding Down ..."

4. Abandoned to the State: Cruelty and Neglect in Russian Orphanages by Kathleen Hunt (1999)
"Bom with Down syndrome, she had been restrained from the neck down in a cloth sack, and apparently left to die. Koloskov filmed Irina's deathly figure and ..."

5. Guide to Clinical Preventive Services: Report of the U. S. Preventive by DIANE Publishing Company (1996)
"Screening for Down syndrome RECOMMENDATION The offering of amniocentesis or chorionic villus sampling (CVS) for chromosome studies is recommended for ..."

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