Lexic.us

Definition of Immunosuppression

1. Noun. Lowering the body's normal immune response to invasion by foreign substances; can be deliberate (as in lowering the immune response to prevent rejection of a transplanted organ) or incidental (as a side effect of radiotherapy or chemotherapy for cancer).

Definition of Immunosuppression

1. Noun. (immunology medicine) The active medical suppression of the immune response. ¹

¹ Source: wiktionary.com

Medical Definition of Immunosuppression

1. This occurs when T and/or B clones of lymphocytes are depleted in size or suppressed in their reactivity, expansion or differentiation. It may arise from activation of specific or non-specific T suppressor lymphocytes of either T or B clones or by drugs that have generalised effects on most or all T or B lymphocytes. Cyclosporin A and FK506 act on T-cells, as does antilymphocyte serum, alkylating agents such as cyclophosphamide are less specific in their action and damage DNA replication, while base analogues interfering with guanine metabolism act in a similar way. See: immunophilin. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Immunosuppression

Literary usage of Immunosuppression

Below you will find example usage of this term as found in modern and/or classical literature:

1. Mineral Requirements for Military Personnel: Levels Needed for Cognitive And by Food and Nutrition Board, Committee on Military Nutrition Research, National Academy of Sciences (U.S.) (2006)
"Physical Activity and Tyrosine Supplementation: Two Effective Interventions Against Stress-Induced Immunosuppression Monika Fleshner University of Colorado, ..."

2. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"Brevetoxin, it was suggested, could induce immunosuppression in exposed dolphins, making them susceptible to the observed opportunistic infections. ..."

3. Alcohols Effect on Organ Function edited by Dianne M. Welsh (1997)
"Moreover, treatment with a protein factor that stimulates neutrophil production ameliorated the alcohol-induced immunosuppression by recruiting more ..."

4. Health Information for International Travel edited by Rosamond R. Dewart (1999)
"Immunosuppression increases the risk for vaccine-associated paralytic polio. OPV should not be given to immunosuppressed individuals or household contacts ..."

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