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Medical Definition of Somogyi effect
1. In diabetes, a rebound phenomenon of reactive hyperglycaemia in response to a preceding period of relative hypoglycaemia that has increased secretion of hyperglycaemic agents (epinephrine, norepinephrine, glucagon, cortisol, and growth hormone); described in diabetic patients given too much insulin who developed unrecognised nocturnal hypoglycaemia that made them hyperglycaemic (suggesting insufficient insulin) when tested the next morning. (05 Mar 2000)
Lexicographical Neighbors of Somogyi Effect
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