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Medical Definition of TNM staging
1. A system of clinicopathologic evaluation of tumours based on the extent of tumour involvement at the primary site (T, followed by a number indicating size and depth of invasion), and lymph node involvement (N) and metastasis (M) each followed by a number starting at 0 for no evident metastasis; numbers used depend on the organ involved and influence the prognosis and choice of treatment. (05 Mar 2000)