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Definition of Acantholysis
1. Noun. A breakdown of a cell layer in the epidermis (as in pemphigus).
Definition of Acantholysis
1. Noun. (medicine) The loss of intercellular connections, resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. ¹
¹ Source: wiktionary.com
Medical Definition of Acantholysis
1. Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris and keratosis follicularis. (12 Dec 1998)
Lexicographical Neighbors of Acantholysis
Literary usage of Acantholysis
Below you will find example usage of this term as found in modern and/or classical literature:
1. The British Journal of Dermatology by British Association of Dermatology (1908)
"The epithelium in immediate juxtaposition with these plugs is seen to be altered ;
acantholysis takes place, resulting in the production of the so-called ..."
2. Edinburgh Medical Journal (1907)
"The granular layer was thick, with abundant kerato-hyaline, hut the mucous layer
exhibited an acantholysis, the connecting cell filaments having disappeared ..."
3. Transactions by Association for Studies in the Conservation of Historic Buildings (Great Britain) (1907)
"The old view of Auspitz, who saw in a sudden disintegration of the prickle cell
layer the chief pathologic process, and therefore called it an acantholysis, ..."
4. Smokeless Tobacco Or Health: An International Perspective by DIANE Publishing Company (1995)
"The changes represented acantholysis and separation of epithelial strata, cell
shrinkage, and nuclear pyknosis. It is notable that the in vitro appearances ..."
5. A Treatise on diseases of the skin for advanced students and practitioners by Henry Weightman Stelwagon (1916)
"... applications are usually efficacious in its treatment. EPIDERMOLYSIS BULLOSA
Synonyms.—Epidermolysis bullosa hereditaria; acantholysis bullosa ..."
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