Medical Definition of Addition-deletion mutation

1. A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000)

Lexicographical Neighbors of Addition-deletion Mutation

addictology
addicts
addies
adding
adding machine
adding up
addio
addios
addisonian
addisonian anaemia
addisonian crisis
addisonian syndrome
additament
additaments
addition
addition-deletion mutation (current term)
addition compound
addition mutation
addition polymer
addition polymerisation
addition polymerization
addition reaction
additional
additionalities
additionality
additionally
additionals
additionary
additions
addititious

Other Resources:

Search for Addition-deletion mutation on Dictionary.com!Search for Addition-deletion mutation on Thesaurus.com!Search for Addition-deletion mutation on Google!Search for Addition-deletion mutation on Wikipedia!

Search