Lexic.us

¹ Source: wiktionary.com

Definition of Allosteric

1. [adj]

Medical Definition of Allosteric

1. Of a binding site in a protein, usually an enzyme. The catalytic function of an enzyme may be modified by interaction with small molecules, not only at the active site, but also at a spatially distinct (allosteric) site of different specificity. Of a protein, a protein possessing such a site. An allosteric effector is a molecule bound at such a site that increases or decreases the activity of the enzyme. This entry appears with permission from the Dictionary of Cell and Molecular Biology (22 Feb 2008)

Lexicographical Neighbors of Allosteric

Literary usage of Allosteric

Below you will find example usage of this term as found in modern and/or classical literature:

1. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"The IC50 of hexamethonium was 20 X 10(-5) M. At 10(-4) M, W84 did not affect the dissociation rate of (-)(3H)nicotine, suggesting a lack of allosteric ..."

2. Molecular Neurobiology: Proceedings of the Second Nimh Conference by Steven Zalcman (1995)
"Binding of allosteric ligands causes a conformational change of the lid to open or close the active site. ..."

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