Medical Definition of Antibody diversity

1. The phenomenon of immense variability characteristic of antibodies, which enables the immune system to react specifically against the essentially unlimited kinds of antigens it encounters. Antibody diversity is accounted for by three main theories: 1) the germ line theory, which holds that each antibody-producing cell has genes coding for all possible antibody specificities, but expresses only the one stimulated by antigen; 2) the somatic mutation theory, which holds that antibody-producing cells contain only a few genes, which produce antibody diversity by mutation; and 3) the gene rearrangement theory, which holds that antibody diversity is generated by the rearrangement of variable region gene segments during the differentiation of the antibody-producing cells. (12 Dec 1998)



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Lexicographical Neighbors of Antibody Diversity

antiblast
antibleeding
antiblennorrhagic
antiblister
antiblue
antibodies
antibody
antibody-dependent cell cytotoxicity
antibody-dependent enhancement
antibody-forming cell
antibody affinity
antibody aldolase
antibody combining site
antibody deficiency disease
antibody deficiency syndrome
antibody diversity (current term)
antibody excess
antibody induced lysis
antibody producing cell
antibody specificity
antibody technology
antibomb
antibonding
antibonding orbital
antibonus
antiboss
antibot
antibots
antibottom
antibound

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