Definition of Carotenoids

1. carotenoid [n] - See also: carotenoid

Medical Definition of Carotenoids

1. Generic term for a class of carotenes and their oxygenated derivatives (xanthophylls) consisting of 8 isoprenoid units joined so that the orientation of these units is reversed at the centre, placing the two central methyl groups in a 1,6 relationship in contrast to the 1,5 of the others. All carotenoids may be formally derived from the acyclic C40H56 structure (part IA, known as lycopene, of the accompanying group of structures) with its long central chain of conjugated double bonds by hydrogenation, dehydrogenation, oxidation, cyclization, or combinations of these. Included as carotenoids are some compounds arising from certain rearrangements or degradations of the carbon skeleton (structure IB), but not retinol and related C20 compounds. The nine-carbon end-groups may be acyclic with 1,2 and 5,6 double bonds (as in structure IA) or cyclohexanes with a single double bond at 5,6 or 5,4, or cyclopentanes or aryl groups; these are now designated by Greek letter prefixes (illustrated in part II of the accompanying group of structures) preceding "carotene" (a and d, which are used in the trivial names alpha-carotene and d-carotene, are not used for that reason). Suffixes (-oic acid, -oate, -al, -one, -ol) indicate certain oxygen-containing groups (acid, ester, aldehyde, ketone, alcohol); all other substitutions appear as prefixes (alkoxy-, epoxy-, hydro-, etc.). The configuration about all double bonds is trans unless cis and locant numbers appear. The prefix retro-is used to indicate a shift of one position of all single and double bonds; apo-indicates shortening of the molecule. Many carotenoids have anticancer activities. (05 Mar 2000)

Lexicographical Neighbors of Carotenoids

caromel
caromels
caroming
caroms
carotenaemia
carotenase
carotene
carotene
carotenemia
carotenes
carotene oxidase
carotenoderma
carotenoid
carotenoid
carotenoids (current term)
carotenoids (current term)
carotenoprotein
carotenosis cutis
Carothers
carotic
caroticoclinoid ligament
caroticotympanic
caroticotympanic arteries
caroticotympanic canaliculi
caroticotympanic nerve
carotid
carotid
carotid-cavernous fistula
carotid-cavernous sinus fistula
carotid-vertebral artery anastomoses

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