Medical Definition of Chromosome walking

1. A procedure to find and sequence a gene whose approximate position in a chromosome is known by classical genetic linkage studies. Starting with the known sequence of a gene shown by classical genetics to be near to the novel gene, new clones are picked from a genomic library by hybridisation with a short probe generated from the appropriate end of the known sequence. The new clones are then sequenced, new probes generated and the process repeated until the gene of interest is reached. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)



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Lexicographical Neighbors of Chromosome Walking

chromosome disorder
chromosome map
chromosome mapping
chromosome mosaicism
chromosome painting
chromosome pairing
chromosome puffs
chromosome rosette
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chromosome satellite
chromosome segregation
chromosome synapsis
chromosome translocation
chromosome walking (current term)
chromosomes
chromosomes in multiple miscarriages
chromosonal disorder
chromosphere
chromospheres
chromospheric
chromospherically
chromostereopsis
chromotherapeutic
chromotherapies
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chromotherapists
chromotherapy
chromotoxic

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