Lexic.us

Definition of Collagenase

1. Noun. Any enzyme that catalyzes the hydrolysis of collagen and gelatin.

Definition of Collagenase

1. Noun. (biology) An enzyme that breaks the peptide bonds in collagen. ¹

¹ Source: wiktionary.com

Definition of Collagenase

1. [n -S]

Medical Definition of Collagenase

1. Proteolytic enzyme capable of breaking native collagen. Once the initial cleavage is made, less specific proteases will complete the degradation. Collagenases from mammalian cells are metallo enzymes and are collagen type specific. May be released in latent (proenzyme) form into tissues and require activation by other proteases before they will degrade fibrillar matrix. Bacterial collagenases are used in tissue disruption for cell harvesting. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Collagenase

Literary usage of Collagenase

Below you will find example usage of this term as found in modern and/or classical literature:

1. Science by American Association for the Advancement of Science (1883)
"Finally, in his examination of the tadpole-collagenase fragments he was able to ... Piez also reported the use of bacterial collagenase as an aid in the ..."

2. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"Preliminary characterisation of the bronchoalveolar lavage collagenase ... Of these, one had increased neutrophils and two had increased collagenase ..."

3. Proceedings of the Society for Experimental Biology and Medicine (1903)
"0.1 mg/ml collagenase in Tris buffer pH 7.5 or in Vis M phosphate 35.9 ± 1.2(70.2 ±2.5) 5.0 ± 3.5 (69.7 ± 3.4) 7.6 ±4.7 (72.1 ± 3.2) 0.0(76.5 ±4.1) 5.8 ±3.6 ..."

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