Definition of Conn's syndrome
1. Noun. Disturbances in saltwater balance and symptoms of weakness and muscular cramps and twitching and convulsions and sometimes paralysis; usually caused by a benign tumor of the cortex of the adrenal gland that leads to excess secretion of aldosterone.
Medical Definition of Conn's syndrome
Overproduction of the hormone aldosterone by a tumour containing tissue like that in the outer portion (cortex) of the adrenal gland.
The excess aldosterone results in low potassium levels (hypokalaemia), underacidity of the body (alkalosis), muscle weakness, excess thirst (polydipsia), excess urination (polyuria), and high blood pressure (hypertension). Also called primary aldosteronism and hyperaldosteronism.
Named after the American physician Jerome W. Conn.
(12 Dec 1998)
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