Definition of Cytotoxicity

1. Noun. The degree to which something is toxic to living cells.

Generic synonyms: Toxicity

Definition of Cytotoxicity

1. Noun. the state of being toxic to cells ¹

¹ Source: wiktionary.com

Definition of Cytotoxicity

1. [n -TIES]

Medical Definition of Cytotoxicity

1. The quality or state of being cytotoxic. Antibody-dependent cell-mediated cytotoxicity (ADCC), a form of lymphocyte-mediated cytotoxicity that functions only if antibodies are bound to the target cell. Lymphocyte-mediated cytotoxicity, the toxic or lytic activity of T-lymphocytes, which may or may not be mediated by antibodies. Cytotoxic T lymphocytes may cause lysis of cells by production of cytolytic proteins such as perforin. B-cells may cause lysis of cells by antibody-complement binding to a target cell. Natural killer cells are cytotoxic without prior sensitization. Toxicity by lymphocytes may also be mediated by antibodies; there are three kinds of cytotoxic T-lymphocytes: those that are antigen-specific as a result of previous allergization (immunization), killer cells, and natural killer cells. See: antibody-dependent cell-mediated cytotoxicity. (05 Mar 2000)

Lexicographical Neighbors of Cytotoxicity

cytotherapy
cytothesis
cytotonic
cytotoxic
cytotoxic T-cell
cytotoxic T cell
cytotoxic T cells
cytotoxic T lymphocyte-specific serine protease
cytotoxic cell
cytotoxic drug
cytotoxic drugs
cytotoxic reaction
cytotoxic t-lymphocyte
cytotoxically
cytotoxicities
cytotoxicity (current term)
cytotoxin
cytotoxins
cytotrophoblast
cytotrophoblastic cells
cytotrophoblastic shell
cytotropic
cytotropic antibody
cytotropic antibody test
cytotropism
cytotype
cytozoic
cytozoon
cytozyme
cytula

Literary usage of Cytotoxicity

Below you will find example usage of this term as found in modern and/or classical literature:

1. Proceedings of the Scientific Workshop on the Health Effects of Electric and by Philip J. Bierbaum (1994)
"Lyle and co-workers (1988) detected a statistically significant 25 percent inhibition of allogeneic cytotoxicity of B-lymphoma target cells by murine ..."

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