Lexic.us

Definition of Diazoxide

1. Noun. Vasodilator (trade name Hyperstat) used to treat severe hypertension.

Definition of Diazoxide

1. Noun. A potassium channel activator which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions, used as a vasodilator to treat hypertension and in diabetes to decrease the secretion of insulin. ¹

¹ Source: wiktionary.com

Medical Definition of Diazoxide

1. A peripheral vasodilator that reduces blood pressure. Diazoxide also has antidiuretic and hypoglycaemic effects. Pharmacological action: antihypertensive agents, diuretics, thiazide, vasodilator agents. Chemical name: 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide (12 Dec 1998)

Lexicographical Neighbors of Diazoxide

Literary usage of Diazoxide

Below you will find example usage of this term as found in modern and/or classical literature:

1. Proceedings of the Society for Experimental Biology and Medicine (1903)
"162(1979) trie Inhibitory Polypeptide, Insulin, and Glucose Changes Produced by Growth Hormone, Prednisolone, Glucagon, Insulin, Fasting, or diazoxide ..."

2. The Chemical News and Journal of Industrial Science (1902)
"In this case, a diazoxide, — CH30 may be formed as an intermediate produit, but this has not yet been isolated. The displacing of the nitro-group in the two ..."

3. Diabetes in America by Ronald Aubert (1996)
"Furthermore, diazoxide, a non-diuretic thiazide, has pronounced p-cell inhibitory as well as peripheral ef- Table 5.4 Sites of Action of Drugs or Agents ..."

4. Journal of the American Chemical Society by American Chemical Society (1914)
"amine obtained by the reduction of the nitro compound may, under suitable precautions, react with nitrous acid to give a diazoxide. ..."

5. Review of American Chemical Research by Massachusetts Institute of Technology, Arthur Amos Noyes, William Albert Noyes (1904)
"... acid is diazotized, treated with alkali carbonates, and the naphthalene 2-i-diazoxide-5-7-disulphonic acid thus formed is combined with /?-naphthol. ..."

6. 5th Report Of The Joint National Committee On Detection, Evaluation, And by DIANE Publishing Company (2004)
"Intravenous hydralazine is effective and has been used safely in pregnancy.83 Limited data are available on the use of diazoxide, labetalol, and clonidine. ..."

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