Definition of Didanosine
1. Noun. An antiviral drug used to combat HIV infection.
Definition of Didanosine
1. Noun. 2',3'-dideoxyinosine, a reverse transcriptase inhibitor effective against HIV. ¹
¹ Source: wiktionary.com
Medical Definition of Didanosine
1.
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddi is then metabolised to dideoxyadenosine triphosphate, its putative active metabolite.
Pharmacological action: anti-HIV agents, antimetabolites, reverse transcriptase inhibitors.
Chemical name: Inosine, 2',3'-dideoxy-
(12 Dec 1998)
Lexicographical Neighbors of Didanosine
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