Medical Definition of Drug-induced lupus

1. An inflammatory autoimmune disorder, similar to lupus, that develops in response to the use of a particular medication. It is characterised by anti-histone antibodies. More benign than the usual disease, with less renal involvement. The syndrome clears after stopping the offending drug. Drugs that are known to cause this reaction include procainamide, isoniazid, sulphasalazine, hydralazine, methyldopa, phenytoin, chlorpromazine and penicillamine. The arthritis, cardiac, pulmonary and systemic features may be present, but the kidney involvement (nephritis) and neurologic disease are rare. Symptoms generally resolve spontaneously after stopping the medication. Complications include myocarditis, pericarditis, thrombocytopenic purpura and infections. (18 Jul 2002)



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Lexicographical Neighbors of Drug-induced Lupus

drudgism
drudgisms
drudgy
drueries
druery
drug
drug-addicted
drug-drug interaction
drug-fast
drug-free
drug-induced cholestasis
drug-induced diarrhoea
drug-induced disease
drug-induced eosinophilic lung disease
drug-induced hepatitis
drug-induced lupus (current term)
drug-induced tremor
drug-ridden
drug abuse
drug activity
drug addict
drug addiction
drug addicts
drug administration routes
drug administration schedule
drug allergy
drug and narcotic control
drug approval
drug baron
drug barons

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