Definition of Gastrin
1. Noun. Polypeptide hormone secreted by the mucous lining of the stomach; when peptides and amino acids are present in the small intestine the secretion of gastric acid is stimulated.
Definition of Gastrin
1. Noun. (hormone) A hormone that stimulates the production of gastric acid in the stomach ¹
¹ Source: wiktionary.com
Definition of Gastrin
1. a hormone [n -S] - See also: hormone
Medical Definition of Gastrin
1.
A group of peptide hormones secreted by the mucosal gut lining of some mammals in response to mechanical stress or high pH. When there is food in the stomach, these cells secrete gastrin.
Gastrin then stimulates the stomach parietal cells to produce hydrochloric acid. Normally, as stomach pH lowers, gastrin secretion decreases. Gastrin blood levels can be determined to be elevated in conditions such as Zollinger-Ellison syndrome and pernicious anaemia.
Several different gastrins have been identified, human gastrin I has 16 amino acids (2116 D). Gastrin is competitively inhibited by cholecystokinin.
(05 Jan 1998)
Lexicographical Neighbors of Gastrin
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