Medical Definition of Hat medium

1. A selective growth medium for animal tissue cells that contains Hypoxanthine, the folate antagonist Aminopterin (or amethopterin) and Thymine. Used for selection of hybrid somatic cell lines, as in the production of monoclonal antibodies. In HAT medium, cells are forced to use these exogenous bases, via the salvage pathways, as their sole source of purines and pyrimidines. Parental cells lacking enzymes such as HGPRT or TK can be eliminated whilst hybrids grow. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)



Hat Medium Pictures

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Lexicographical Neighbors of Hat Medium

HACEK
HACEK group
HACO
HAHO
HAL
HALGI
HALO
HAM
HAMC
HAND
HANE
HANS
HAPE
HAPO
HATO
HAT medium
HAV
HAVRIX
HAZMAT
HB
HBA
HBC
HBD
HBE
HBIG
HBMS
HBO
HBOS
HBV
HBcAb

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