Medical Definition of Lecithin-cholesterol acyltransferase
1.
An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesterol ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anaemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish-eye disease.
Synonym: lecithin acyltransferase.
Acronym: LCAT
(05 Mar 2000)
Lexicographical Neighbors of Lecithin-cholesterol Acyltransferase
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