Lexic.us

Definition of Lidocaine

1. Noun. A local anesthetic (trade names Lidocaine and Xylocaine) used topically on the skin and mucous membranes.

Definition of Lidocaine

1. Noun. (medicine) A local anesthetic that is also used as a antiarrhythmic drug. ¹

¹ Source: wiktionary.com

Definition of Lidocaine

1. [n -S]

Medical Definition of Lidocaine

1. A local anaesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine. Pharmacological action: anaesthetics, local, anti-arrhythmia agents. Decreases automaticity, depresses conduction in reentrant pathways and may raise fibrillation threshold, especially in combination with bretylium. Uses: The drug of first choice for ventricular arrhythmias, ventricular ectopy, and wide complex tachycardias of unknown origin. Dose: 1-1.5 mg/kg IV bolus, followed by additional 0.5-1.5 mg/kg every 5-10 min to a total of 3 mg/kg. Can be administered via the endotracheal tube. Use 2 to 2.5 times the intravenous dose. Upon return of circulation, use continuous infusion at 2 - 4 mg/min. Reduce the maintenance dose if decreased cardiac output or hepatic failure or more than 70 years of age. Potential complications: dizziness, drowsiness, disorientation, seizures, hypotension - causes vasodilation; myocardial depression at higher concentrations; heart block - only rarely seen with high levels. Chemical name: 2-(diethylamino)-N-(2,6-dimethylphenyl)-acetamide (15 Mar 2000)

Lexicographical Neighbors of Lidocaine

Literary usage of Lidocaine

Below you will find example usage of this term as found in modern and/or classical literature:

1. Problems of Drug Dependence: Proceedings of the 58th Annual Scientific Meeting by Louie S. Harrie (1999)
"The present study investigated whether a cocaine preference also could be established by the avoidance of a concentrated lidocaine solution, rather than by ..."

2. Animal Euthanasia: Bibliography, January 1990-November 1997 edited by Michael D. Kreger (1999)
"It was concluded that pentobarbital in combination with lidocaine was ... Descriptors: dogs; physiology; lidocaine; Pentobarbital 41. ..."

3. Code of Federal Regulations, Title 21, Food and Drugs, Pt. 800-1299, Revised by Food and Drug Administration (FDA) Staff (2005)
"Measurements obtained by this device are used in the diagnosis and treatment of lidocaine overdose on in monitoring levels of lidocaine to ensure ..."

4. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"In the present study this effect of nicotine was attenuated (to about 25% of control response) by injection of lidocaine into the nucleus ..."

5. Cocaine: Pharmacology, Effects, and Treatment of Abuse edited by John Grabowski (1994)
"All doses of lidocaine and 16 and 32 mg procaine were identified as placebo. There has, however, been one report of subjects giving similar ratings of ..."

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