Definition of Monoamine oxidase inhibitor

1. Noun. Any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate.

Exact synonyms: Maoi
Generic synonyms: Antidepressant, Antidepressant Drug
Specialized synonyms: Iproclozide, Isocarboxazid, Marplan, Nardil, Phenelzine, Tranylcypromine



Medical Definition of Monoamine oxidase inhibitor

1. A drug that interferes with the action of monoamine oxidase, slowing the breakdown of certain neurotransmitters. Used in the treatment of depression. Monoamine oxidase inhibitors are a group of antidepressant drugs that prevent the activity of the enzyme monoamine oxidase in the central nervous system (brain) thus affecting mood. The use of these medications is often restricted due to their severe side effects and drug (and food) interactions. Examples include isocarboxazid, pargyline, selegiline, furazolidone and phenelzine. Acronym: MAOI (26 Mar 1998)

Lexicographical Neighbors of Monoamine Oxidase Inhibitor

monoalkylation
monoalkylations
monoalkynylation
monoallelic
monoallelically
monoalphabetic
monoalphabetically
monoaluminium
monoaluminum
monoamide
monoamides
monoamine
monoamine neurotransmitter
monoamine neurotransmitters
monoamine oxidase
monoamine oxidase inhibitor (current term)
monoamine oxidase inhibitors
monoamine oxidases
monoaminergic
monoamines
monoaminosaccharide
monoaminosaccharides
monoaminuria
monoamniotic
monoandry
monoanionic
monoaromatic
monoaromatics
monoarsenide
monoarthritis

Literary usage of Monoamine oxidase inhibitor

Below you will find example usage of this term as found in modern and/or classical literature:

1. Value of Psychiatric Treatment: Its Efficacy in Severe Mental Disorders edited by Samuel J. Keith (1996)
"Phenelzine is the monoamine oxidase inhibitor most frequently ... 1980) was the most definitive trial of the efficacy of a monoamine oxidase inhibitor. ..."

2. Treatment of Depression edited by Cynthia D. Mulrow (2000)
"... long half-life of fluoxetine, the serotonin syndrome has occurred, even when fluoxetine was started over 2 weeks after a monoamine oxidase inhibitor was ..."

3. Code of Federal Regulations by Food and Drug Administration (FDA) Staff (2005)
""Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, ..."

4. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"Our studies with bright light are consistent with those indicating that heterocyclic antidepressants and a monoamine oxidase inhibitor ..."

5. Drug Labeling In Developing Countries by DIANE Publishing Company (2004)
"... failure to contraindicate the use of a monoamine oxidase inhibitor with the antidepressant fluoxetine); 3. the drug may harm a fetus in a pregnant woman ..."

6. Assessment and Treatment of Patients With Coexisting Mental Illness and by Richard Ries (1996)
"The interaction of stimulants in a person taking monoamine oxidase inhibitor antidepressants can lead to a life-threatening hypertensive crisis. ..."

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