Definition of Nucleotide

1. Noun. A phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA).

Definition of Nucleotide

1. Noun. (biochemistry) the monomer comprising DNA or RNA biopolymer molecules. Each nucleotide consists of a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine; a five-carbon pentose sugar (deoxyribose in DNA or ribose in RNA); and a phosphate group. ¹

¹ Source:

Definition of Nucleotide

1. [n -S]

Medical Definition of Nucleotide

1. Phosphate esters of nucleosides. The metabolic precursors of nucleic acids are monoesters with phosphate on carbon 5 of the pentose (known as 5' to distinguish sugar from base numbering). However many other structures, such as adenosine 3'5' cyclic monophosphate (cAMP) and molecules with 2 or 3 phosphates are also called nucleotides. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Nucleotide

nucleoskeletal DNA
nucleotide (current term)
nucleotide binding fold
nucleotide deaminases
nucleotide deletion
nucleotide mapping
nucleotide pair
nucleotide phosphotransferase
nucleotide pyrophosphate transferase
nucleus accumbens

Literary usage of Nucleotide

Below you will find example usage of this term as found in modern and/or classical literature:

1. Manual of Patent Examining Procedure edited by J. Michael Thesz (1997)
"2423 Symbols and Format to be Used for nucleotide and/or Amino Acid Sequence Data 37 CFR 1.822 Symbols and format to be used for nucleotide and/or omino ..."

2. Molecular Markers in Plant Genome Analysis: Sponsored CRIS/ICAR Projects and by Andrew Kalinski (1995)
"Chloroplast DNA and nuclear ribosomal spacer region will be analyzed for variation in nucleotide sequences and structural organization using ..."

3. Assessing the Human Health Risks of Trichloroethylene: Key Scientific Issues by National Research Council (U.S.) (2006)
"Of the validated single nucleotide polymorphisms, 40 occur in introns, ... For many single nucleotide polymorphisms, the functional significance, if any, ..."

4. Biotechnology: Plant Nutrition: A Bibliography, January 1988-April 1993 by Janet Saunders (1994)
"M65 nucleotide sequence and protein products of two new ... P62 nucleotide sequence of Rhizobium meliloti GR4 insertion sequence ..."

5. Hantaviruses: Emerging Viral Diseases edited by J. S. Mackenzie (1999)
"Other examples include 1 of 139 and 2 of 139 nucleotide sequence differences ... The 139 nucleotide fragments of these viruses have up to 10.1% nucleotide ..."

6. Gene Expression in Horticultural Crops: Bibliography January 1991-October 1992 by Robert D. Warmbrodt (1995)
"132 NAL Call No: 450 P692 nucleotide sequence and spatial expression pattern of a drought- and abscisic acid-induced gene of tomato. Plant, AL; Cohen, A.; ..."

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