Medical Definition of Oxalosuccinic carboxylase

1. An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (the NADP+ enzyme is EC 1.1.1.42.) Chemical name: Isocitrate:NAD+ oxidoreductase (decarboxylating) Registry number: EC 1.1.1.41 (12 Dec 1998)



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Lexicographical Neighbors of Oxalosuccinic Carboxylase

oxalis
oxalises
oxalite
oxalites
oxalo
oxalo-
oxaloacetate
oxaloacetate tautomerase
oxaloacetate transacetase
oxaloacetates
oxaloacetic acid
oxalocrotonate
oxalocrotonic acid
oxalosis
oxalosuccinic acid
oxalosuccinic carboxylase (current term)
oxalourea
oxaluramide
oxalurate
oxalurates
oxaluria
oxaluric
oxaluric acid
oxalyl
oxalyl CoA decarboxylase
oxalyl chloride
oxalylglycine
oxalylurea
oxamate
oxamate carbamoyltransferase

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