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Medical Definition of Perimenopause
1. The three to five year period prior to menopause during which oestrogen levels begin to drop.Studies have revealed that oestrogen replacement therapy may be more effective if started during perimenopause, particularly in preventing bone loss, which immediately accelerates as soon as overall oestrogen is reduced. For the bone-saving benefits of oestrogen replacement therapy to be seen during the period between age 70 and 80, when the risk of breakage is high, it apparently must be begun during perimenopause and continued for many years. (05 Mar 2000)
Lexicographical Neighbors of Perimenopause
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