Definition of Selectin
1. Noun. (biochemistry) Any of a group of transmembrane glycoproteins important in cell adhesion ¹
¹ Source: wiktionary.com
Medical Definition of Selectin
Group of cell adhesion molecules that bid to carbohydrates via a lectin like domain. The name is derived from select and lectin.
They are integral membrane glycoproteins with an N terminal, C type lectin domain, followed by an EGF like domain, a variable number of repeats of the short consensus sequence of complement regulatory proteins and a single transmembrane domain.
Three selectins have been identified and are distinguished by capital letters based on the source of the original identification i.e. E selectin, L selectin and P selectin.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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