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Definition of Take a powder
1. Verb. Disappear without notifying anyone (idiom).
Definition of Take a powder
1. Verb. (idiomatic US colloquial) To leave in a hurry; run away; scram; depart without taking leave or notifying anyone, often with a connotation of avoiding something unpleasant or shirking responsibility. ¹
¹ Source: wiktionary.com