Medical Definition of Tetrahydrofolate dehydrogenase

1. An enzyme of the oxidoreductase class that catalyses the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. Chemical name: 5,6,7,8-Tetrahydrofolate:NADP+ oxidoreductase Registry number: EC 1.5.1.3 (12 Dec 1998)



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Lexicographical Neighbors of Tetrahydrofolate Dehydrogenase

tetrahydrides
tetrahydro
tetrahydro-
tetrahydrobiopterin
tetrahydroborate
tetrahydroborates
tetrahydrocannabinol
tetrahydrocannabivarin
tetrahydrocannabivarol
tetrahydrocannibanol
tetrahydrochloride
tetrahydrocortisol
tetrahydrocortisone
tetrahydrodipicolinic acid
tetrahydrofolate
tetrahydrofolate dehydrogenase (current term)
tetrahydrofolate methyltransferase
tetrahydrofolates
tetrahydrofolic acid
tetrahydrofuran
tetrahydrofurans
tetrahydrogenated
tetrahydrogestrinone
tetrahydrogestrinones
tetrahydroharmine
tetrahydroimidazole
tetrahydroisoquinoline
tetrahydroisoquinolines
tetrahydrolipstatin
tetrahydromethanopterin

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