Definition of Troponin
1. Noun. (protein medicine) A complex of three regulatory proteins that is integral to muscle contraction in skeletal and cardiac muscle, or any member of this complex. The level of troponin in the blood is often used as an indicator of heart damage. ¹
¹ Source: wiktionary.com
Definition of Troponin
1. a protein of muscle [n -S]
Medical Definition of Troponin
1.
Complex of three proteins, Troponins C, I, & T, associated with tropomyosin and actin on the thin filament of striated muscle, upon which it confers calcium sensitivity. There is one troponin complex per tropomyosin. Troponin C (18 kD) binds calcium ions reversibly, has a variable number of EF hand motifs and is the least variable of the subunits. TnC binds TnI & TnT, but not actin. Troponin I (23 kD) binds to actin and at 1:1 stoichiometry can inhibit the actin myosin interaction on its own. Troponin T (37 kD) binds strongly to tropomyosin.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
Lexicographical Neighbors of Troponin
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