Medical Definition of Zinostatin

1. An antitumour isolate from the culture filtrate of the f-41 variant of streptomyces carzinostaticus. It is a protein of known amino acid sequence with a molecular weight of approximately 11,500 and possessing a regulatory function on the metabolism of DNA. In this process, that is first an inhibition of DNA biosynthesis followed by the degradation of DNA, zinostatin functions in a manner analogous to that of the much higher molecular weight antibiotic mitomycin c. Zinostatin is also a potent cytostatic agent active against gram-positive organisms. Pharmacological action: antibiotics, antineoplastic, nucleic acid synthesis inhibitors. Chemical name: Neocarzinostatin (12 Dec 1998)

Lexicographical Neighbors of Zinostatin

Zinn's corona
Zinn's ligament
Zinn's membrane
Zinn's ring
Zinn's tendon
Zinn's vascular circle
Zinn's zonule
Zinnemann
zinnia
zinnia
zinnias
Zinnia acerosa
Zinnia grandiflora
zinnwaldite
zinnwaldite
zinostatin (current term)
zins
zinsang
zinsser
Zinsser
Zinzendorf
zinziberaceous
Zion
Zionism
Zionist
Zionist movement
Zion National Park
zip
zip-fastener
Ziphiidae

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