Medical Definition of Lymphocyte transformation
1.
The change in morphology and behaviour of lymphocytes exposed to a mitogen or to an antigen to which they have been primed. The result is the production of lymphoblasts, cells that are actively engaged in protein synthesis and that divide to form effector populations. Should not be confused with transformation of the type associated with oncogenic viruses and activation is therefore perhaps a better term.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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