Medical Definition of DNA topoisomerase

1. An enzyme capable of altering the degree of supercoiling of double stranded DNA molecules. Various topoisomerases can increase or relax supercoiling, convert single stranded rings to intertwined double stranded rings, tie and untie knots in single stranded and duplex rings, catenate and decatenate duplex rings. Topoisomerase II of E. Coli = gyrase. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

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Lexicographical Neighbors of DNA Topoisomerase

DNA replication
DNA restriction-modification enzymes
DNA restriction enzymes
DNA reverse gyrase
DNA sequence
DNA sequence analysis
DNA sequences
DNA sequencing
DNA shearing
DNA snippet
DNA snippets
DNA supercoiling
DNA synaptase
DNA synthesis
DNA synthesiser
DNA topoisomerase (current term)
DNA topoisomerase (ATP-hydrolysing)
DNA transfection
DNA tumour virus
DNA tumour viruses
DNA twisting
DNA typing
DNA unwinding protein
DNA virus
DNA viruses
DNA writhing
DNAa gene
DNAb gene
DNAe gene
DNAf gene

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