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Definition of Iroquois league
1. Noun. A league of Iroquois tribes including originally the Mohawk, Oneida, Onondaga, Cayuga and Seneca (the Five Nations); after 1722 they were joined by the Tuscarora (the Six Nations). 
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1. Noun. A league of Iroquois tribes including originally the Mohawk, Oneida, Onondaga, Cayuga and Seneca (the Five Nations); after 1722 they were joined by the Tuscarora (the Six Nations).