Medical Definition of Pelizaeus-Merzbacher disease

1. A sudanophilic leukodystrophy with a tigroid appearance of the myelin resulting from patchy demyelination. Type 1-classic, nystagmus and tremor appearing in the first few months of life, followed by slow motor development sometimes with choreoathetosis, spasticity, optic atrophy and seizures, with death in early adulthood, X-linked recessive inheritance; type 2-contralateral form with death in months to years after birth, X-linked recessive inheritance; type 3-transitional, with death in the first decade; type 4-adult form associated with involuntary movements, ataxia and hyperreflexia, but without nystagmus; type 5-variant forms. Cockayne is sometimes included as a sixth form. Synonym: Merzbacher-Pelizaeus disease. (05 Mar 2000)

Lexicographical Neighbors of Pelizaeus-Merzbacher Disease

Pelasgic
Pele
Pele-type
Pelecanidae
Pelecanoididae
Pelecanus
Pelecanus erythrorhynchos
Pelecanus onocrotalus
Peleg
Peleus
Pelew
Pelham
Pelham Grenville Wodehouse
Pelican State
Pelizaeus-Merzbacher disease (current term)
Pell's equation
Pella
Pellaea
Pellaea andromedifolia
Pellaea atropurpurea
Pellaea mucronata
Pellaea ornithopus
Pellaea rotundifolia
Pellegrini's disease
Pellegrini-Stieda disease
Pellicularia
Pellicularia filamentosa
Pellicularia koleroga
Pellizzi's syndrome

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