Definition of Antigen

1. Noun. Any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies).

Generic synonyms: Substance
Specialized synonyms: Immunizing Agent, Immunogen, Agglutinogen, Fetoprotein, Foetoprotein, Anatoxin, Toxoid, Rh, Rh Factor, Rhesus Factor
Category relationships: Immunology
Terms within: Antigenic Determinant, Determinant, Epitope
Derivative terms: Antigenic

Definition of Antigen

1. Noun. (immunology) A substance that induces an immune response, usually foreign. ¹

¹ Source:

Definition of Antigen

1. a substance that stimulates the production of antibodies [n -S]

Medical Definition of Antigen

1. A protein molecule that often protrudes from the surface of a cell that can induce an immune response. The epitope is the part of the molecule that is responsible for this feature, whereas the carrier molecule results in the activity as an antigen. Usually antigens are foreign to the host animal in which they produce a response. (18 Nov 2007)

Antigen Pictures

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Lexicographical Neighbors of Antigen

antigen (current term)
antigen-antibody complex
antigen-antibody reaction
antigen-binding site
antigen-combining site
antigen-presenting cell
antigen-responsive cell
antigen-sensitive cell
antigen excess
antigen interferon
antigen presentation
antigen processing
antigen shift
antigen unit

Literary usage of Antigen

Below you will find example usage of this term as found in modern and/or classical literature:

1. Science by American Association for the Advancement of Science (1883)
"antigen interacting with the receptor (bound configuration) paralyzed a cell and that two molecules of antigen interacting with one receptor (stretched ..."

2. The Medical Clinics of North America by Michael C. Fiore, Stephen S. Entman, Charles B. Rush (1921)
"antigen No. 1 4+ antigen No. 2 4+ antigen No. 3 4 + antigen No. 1 4+ antigen No. 2 4+ antigen No. 3 4 + antigen No. 1 3 + antigen No. 2 1 + antigen No. ..."

3. Chemical Abstracts by American Chemical Society (1916)
"tially desensitized by the injection of antigen can be killed only by the use of much ... The increased dose of antigen necessary to elicit an anaphylactic ..."

4. Pathogenic microorganisms by William Hallock Park (1920)
"Standardization of antigen.—There are two requirements for a good antigen, (1) a long range and (2) specificity.1 The range of an antigen is determined by ..."

5. Understanding the Immune System by Lydia Woods Schindler (1994)
"antigen antigen-specific Receptor B cell's antigen-specific receptor, an antibody embedded on the cell's surface, recognizes antigen in its natural state. ..."

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