Definition of Baclofen

1. Noun. A particular drug used to control spasms. It is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early stages of use for the treatment of alcoholism. ¹



¹ Source: wiktionary.com

Definition of Baclofen

1. a muscle relaxant [n -S]

Medical Definition of Baclofen

1. A gaba derivative that is a specific agonist at gaba-b receptors (receptors, gaba-b). It is used in the treatment of spasticity, especially that due to spinal cord damage. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission. Pharmacological action: gaba agonists, muscle relaxants, central. Chemical name: Benzenepropanoic acid, beta-(aminomethyl)-4-chloro- (12 Dec 1998)

Baclofen Pictures

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Lexicographical Neighbors of Baclofen

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backword
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backwraps
backy
backyard
backyard cricket
backyards
baclava
baclavas
baclofen (current term)
baclofens
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bacmids
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bacon
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baconburger

Literary usage of Baclofen

Below you will find example usage of this term as found in modern and/or classical literature:

1. Molecular Neurobiology: Proceedings of the Second Nimh Conference by Steven Zalcman (1995)
"Characterization of synaptic transmission between sensory neurons and spinal cord cells in vitro and its modulation by baclofen. ..."

2. Problems of Drug Dependence: Proceedings of the 58th Annual Scientific Meeting by Louie S. Harrie (1999)
"At Pizarro Treatment Center, ten cocaine abusers were treated with baclofen, in combination with group counseling (3 hours/week), for up to 16 weeks. ..."

3. Pediatric Drug Research: Studies Conducted Under Best Pharmaceuticals for by Marcia Crosse (2007)
"baclofen was identified by NIH and FNIH as the highest priority on-patent drug that ... NIH requested proposals for the study of baclofen and has selected a ..."

4. Stress, Gender, and Alcohol-Seeking Behavior edited by Walter A. Hunt, Sam Zakhari (1996)
"Excitatory amino acid (EAA) innerva- Stimulation of GABAB receptors by tion of the VTA arises from a number microinjecting baclofen into the VTA of brain ..."

5. Approved Drug Products with Therapeutic Evaluationsby DIANE Publishing Company by DIANE Publishing Company (1995)
"NAME Generic/Chemical TN=Trade Name baclofen TN= LIORESAL INTRATHECAL baclofen TN= baclofen TN= LIORESAL INTRATHECAL BENZOATE AND PHENYLACETATE TN= ..."

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