Definition of Factor xii
1. Noun. Coagulation factor whose deficiency results in prolongation of clotting time of venous blood.
Medical Definition of Factor xii
1.
Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor xii to xiia. Deficiency of factor xii, also called the hageman trait, leads to increased incidence of thromboembolic disease.
Chemical name: Blood-coagulation factor XII
(12 Dec 1998)
Lexicographical Neighbors of Factor Xii
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