Lexic.us

Medical Definition of Lead hydroxide stain

1. A stain for electron microscopy; after aldehyde fixation, alkaline lead hydroxide preferentially stains RNA, but after OsO4 fixation, it reacts largely with osmium in tissues to give a general stain; in addition to binding to cytomembranes, it also stains carbohydrates (e.g., glycogen). (05 Mar 2000)

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