Medical Definition of Macrolide 2'-kinase
1.
Inducible intracellular enzyme which inactivates 14-member ring macrolides at the 2'-oh of the d-desosamine moiety; from an erythromycin-resistant strain of E coli; GTP, itp and ATP can also act as donors; mph(2')i is encoded by mpha and mrx, which have been sequenced
Registry number: EC 2.7.1.136
Synonym: oleandomycin 2'-phosphotransferase, macrolide 2'-phosphotransferase, macrolide 2'-phosphotransferase I, mph(2')i
(26 Jun 1999)
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