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Medical Definition of Major depression
1. A clinical syndrome that includes a persistent sad mood or loss of interest in activities that persists for at least 2 weeks in the absence of external precipitants. This should not be confused with a grief reaction (death of loved one). Features may include change in eating habits, insomnia, early morning wakening, lack of interest, depressed mood, fatigue and suicidal thoughts. (27 Sep 1997)
Lexicographical Neighbors of Major Depression
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