Definition of Mast cell

1. Noun. A large connective tissue cell that contains histamine and heparin and serotonin which are released in allergic reactions or in response to injury or inflammation.

Exact synonyms: Labrocyte, Mastocyte
Group relationships: Connective Tissue
Generic synonyms: Somatic Cell, Vegetative Cell



Definition of Mast cell

1. Noun. A resident cell of connective tissue that contains many granules rich in histamine and heparin. ¹

¹ Source: wiktionary.com

Medical Definition of Mast cell

1. Resident cell of connective tissue that contains many granules rich in histamine and heparan sulphate. Release of histamine from mast cells is responsible for the immediate reddening of the skin in a weal and flare response. Very similar to basophils and possibly derived from the same stem cells. Two types of mast cells are now recognised, those from connective tissue and a distinct set of mucosal mast cells, the activities of the latter are T-cell dependent. (05 Jan 1998)

Lexicographical Neighbors of Mast Cell

mast
mast-
mast-cell
mast cell (current term)
mast cell leukaemia
mast cells
mast climbing
mast leukocyte
mast seeding
mastaba
mastabah
mastabahs
mastabas
mastadenitis
mastadenoma
mastadenovirus
mastalgia
mastalgias

Literary usage of Mast cell

Below you will find example usage of this term as found in modern and/or classical literature:

1. Practical Handbook of the Pathology of the Skin: An Introduction to the by John MacLeod Hendrie MacLeod (1903)
"Spindle-shaped mast-cell showing blue nucleus; no intranuclear network or ... Mast-cell shaped like a plasma-cell. t. Mast-cell with nucleus like that of a ..."

2. Understanding the Immune System by Lydia Woods Schindler (1991)
"When an IgE antibody sitting on a mast cell or basophil encounters its specific allergen, the IgE antibody signals the mast cell or basophil to release the ..."

3. A Manual of Clinical Diagnosis by Means of Microscopical and Chemical by Charles Edmund Simon (1904)
"With the latter group the mast-cell granules are colored yellow; with most of the violet ... Methyl-green does not stain the mast-cell granules unless it is ..."

4. A Manual of Clinical Diagnosis by Means of Microscopic and Chemical Methods by Charles Edmund Simon (1907)
"With the latter group the mast- cell granules are colored yellow, with most of the ... Methyl green does not stain the mast-cell granules unless it is ..."

5. The British Journal of Dermatology by British Association of Dermatology (1905)
"The cells may be described as being of two types—(1) the fusiform, well-developed mast-cell, with normal nucleus and a copious granular mantle around it; ..."

6. Diseases of the Skin: A Textbook for Students and Practitioners by J. M. H. MacLeod (1921)
"Spindle-shaped mast-cell with blue nucleus, b. Mast-cell dividing, c. ... Mast-cell. FIG. 5.—Horn-cells which have undergone Hyalin Degeneration. ..."

7. Saint Louis Medical and Surgical Journal (1896)
"Since the other structures which exhibit the mast-cell reaction are not ... First, and this quite often, the mast-cell is surrounded by irregularly ..."

8. Clinical Hematology: A Practical Guide to the Examination of the Blood with by John C. DaCosta (1901)
"The granules of the mast cell show an intense affinity for basic aniline dyes, ... In specimens thus treated the mast cell granules arc of a dark red color, ..."

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