Definition of Oncogene

1. Noun. A gene that disposes normal cells to change into cancerous tumor cells.

Exact synonyms: Transforming Gene
Generic synonyms: Cistron, Factor, Gene

Definition of Oncogene

1. Noun. (oncology genetics) Any gene that contributes to the conversion of a normal cell into a cancerous cell when mutated or expressed at high levels. ¹

¹ Source:

Definition of Oncogene

1. a gene that causes a cell to become cancerous [n -S]

Medical Definition of Oncogene

1. Mutated and/or overexpressed version of a normal gene of animal cells (the proto-oncogene) that in a dominant fashion can release the cell from normal restraints on growth and thus alone or in concert with other changes, convert a cell into a tumour cell. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Oncogene

oncocytic hepatocellular tumour
oncofetal antigens
oncofetal marker
oncogene (current term)
oncogene protein gp140(v-fms)
oncogene protein p21(ras)
oncogene protein p55(v-myc)
oncogene protein p65(gag-jun)
oncogene protein pp60(v-src)
oncogene proteins
oncogene proteins v-abl
oncogene proteins v-erba
oncogene proteins v-erbb
oncogene proteins v-fos
oncogene proteins v-mos

Literary usage of Oncogene

Below you will find example usage of this term as found in modern and/or classical literature:

1. Molecular Neurobiology: Proceedings of the 2nd NIMH Conference by Steven Zalcman (1995)
"We have been studying the regulation and function of the fas proto-oncogene as an example of an immediate-early transcription factor. ..."

2. Smokeless Tobacco Or Health: An International Perspective by DIANE Publishing Company (1993)
"Zhou, DJ, Casey, G., Cline, M J. Amplification of human int-2 in breast cancers and squamous cell carcinomas. oncogene 2: 279-282, 1988. oncogene ..."

3. Biological Effects of Power Line Fields Scientific Advisory Panels Final Report by DIANE Publishing Company (1994)
"oncogene Studies: Molecular Genetic Analysis of Tumor Cells Exposed to Electromagnetic Fields: In order to pursue further the possibility of effects of ..."

4. Environmental Epidemiology by National Research Council (1992)
"Abnormal patterns of oncogene-related protein products were detected both in the biologic ... At the time of the evaluation of oncogene- related proteins, ..."

5. Catalyzing Inquiry at the Interface of Computing and Biology by John C. Wooley, Herbert Lin (2005)
"A specific oncogene can induce changes in the state of downstream genes (ie, genes for which the oncogene is part of their regulatory network) and ..."

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