Definition of Oncogenes

1. Noun. (plural of oncogene) ¹

¹ Source:

Definition of Oncogenes

1. oncogene [n] - See also: oncogene

Medical Definition of Oncogenes

1. Genes which can potentially induce neoplastic transformation. They include genes for growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. When these genes are constitutively expressed after structural and/or regulatory changes, uncontrolled cell proliferation may result. Viral oncogenes have names of the form v-onc; cellular oncogenes (proto-oncogenes) are designated c-onc. (12 Dec 1998)

Lexicographical Neighbors of Oncogenes

oncofetal antigens
oncofetal marker
oncogene protein gp140(v-fms)
oncogene protein p21(ras)
oncogene protein p55(v-myc)
oncogene protein p65(gag-jun)
oncogene protein pp60(v-src)
oncogene proteins
oncogene proteins v-abl
oncogene proteins v-erba
oncogene proteins v-erbb
oncogene proteins v-fos
oncogene proteins v-mos
oncogenes (current term)
oncogenic virus
oncogenic viruses

Literary usage of Oncogenes

Below you will find example usage of this term as found in modern and/or classical literature:

1. Smokeless Tobacco Or Health: An International Perspective by DIANE Publishing Company (1993)
"INTRODUCTION Proto-oncogenes are normal cellular genes known to function in ... When mutated or abnormally expressed, proto-oncogenes can be activated to ..."

2. Useful Knowledge: The American Philosophical Society Millennium Program by Alexander G. Bearn, American Philosophical Society (1999)
"The first are called oncogenes. oncogenes normally function as the accelerators in the ... If you permit me to use automobiles as an analogy, oncogenes are ..."

3. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"The molecular basis of oncogenes and tumor 63. suppressor genes. ... Mutations of the^>53 tumor suppressor gene and ras oncogenes in aflatoxin ..."

4. Novel Systems for the Study of Human Disease: From Basic Research to by OECD Staff, (Paris) Organisation for Economic Co-ope, SourceOECD (Online service) (1998)
"Transgenic mice and knock-out mice as models for genetic lesions in cancer Transgenic mice which express various viral and cellular oncogenes in specific ..."

5. Researching Health Risks by Office of Technology Assessment, United States, Congress (1993)
"Box 7-B-The Biology of oncogenes and Tumor Suppressor Genes During the normal development of an organism, a chemical "conversation" occurs among the ..."

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