Definition of Penicillinase

1. Noun. Enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic.

Exact synonyms: Beta-lactamase
Generic synonyms: Enzyme

Definition of Penicillinase

1. Noun. (biochemistry) A specific type of beta-lactamase showing specificity for penicillins. ¹

¹ Source:

Definition of Penicillinase

1. [n -S]

Medical Definition of Penicillinase

1. Penicillin amino á lactamhydrolase: an enzyme produced by certain bacteria which converts penicillin to an inactive product and thus increases resistance to the antibiotic. A purified preparation from cultures of a strain of Bacillus cereus is used in treatment of reactions to penicillin. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Penicillinase

penicillin G hydrabamine
penicillin G procaine
penicillin G sodium
penicillin N
penicillin O
penicillin V
penicillin V benzathine
penicillin V hydrabamine
penicillin amidase
penicillin penicillium
penicillin phenoxymethyl
penicillin resistance
penicillin v
penicillinase (current term)
penicillinase-resistant antibiotic
penicillium chrysogenum
penicilloic acid
penicilloyl polylysine

Literary usage of Penicillinase

Below you will find example usage of this term as found in modern and/or classical literature:

1. Code of Federal Regulations by Food and Drug Administration (FDA) Staff (2005)
"... cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of beta- lactamase (penicillinase) producing Staphylococcus aureus, ..."

2. Arsenic by Assembly Of Life Sciences, National Academies Press, Assembly of Life Sciences (U.S.), National Academy of Sciences (U.S.) (1977)
"... showed that the penicillinase plasmids, a series of extrachromosomal resistance factors in Staphylococcus aureus, carry determinants of resistance to ..."

3. Biographical Memoirs by National Academy Of Sciences, National Academy of Sciences Staff, Caroline K. McEuen (1980)
"Enzymologia, 10:192-202. 1946 With A. Torriani. Sulla purificazione della penicillinase da Bacterium Coli. Boll. Soc. Ital. Biol. Sper., 22:1. ..."

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