Medical Definition of Peptidase p

1. A hydrolase cleaving C-terminal dipeptides from a variety of substrates, including angiotensin I, which is converted to angiotensin II and histidylleucine. An important step in the metabolism of certain vasopressor agents. It is a chloride-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. Only single dipeptides are released from angiotensin I and bradykinin because of the lack of activity on bonds involving proline. It may also have endopeptidase activity on some substrates. Registry number: EC 3.4.15.1 Synonym: carboxycathepsin, dipeptidyl carboxypeptidase, kinase II, peptidase P. (22 Sep 2002)



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Lexicographical Neighbors of Peptidase P

peptalking
peptalks
peptic
peptic-ulcer
peptic cell
peptic digestion
peptic gland
peptic ulcer
peptic ulcer perforation
peptic ulceration
peptichemio
peptics
peptid
peptidase
peptidase D
peptidase P
peptidases
peptide
peptide N-alpha acetyltransferase
peptide antibiotic lactonase
peptide bond
peptide bonds
peptide chain
peptide chain elongation
peptide chain initiation
peptide chain termination
peptide chains
peptide deformylase
peptide elongation factor tu
peptide elongation factors

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