Definition of Phase i clinical trial
1. Noun. A clinical trial on a few persons to determine the safety of a new drug or invasive medical device; for drugs, dosage or toxicity limits should be obtained.
Medical Definition of Phase i clinical trial
Phase I Clinical Trial Pictures
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Lexicographical Neighbors of Phase I Clinical Trial
Literary usage of Phase i clinical trial
Below you will find example usage of this term as found in modern and/or classical literature:
1. New Developments and Applications in Experimental Design: Selected by Nancy Flournoy, William F. Rosenberger, Weng Kee Wong (1998)
"The objective of a phase I clinical trial is to determine a maximum tolerated dose (MTD), where response is generally dichotomous ("toxicity" or "no ..."
2. Adaptive Designs: Selected Proceedings of a 1992 Joint Ams-Ims-Siam Summer by Nancy Flournoy, William F. Rosenberger, American Mathematical Society, Institute of Mathematical Statistics (1995)
"... response function is equal to the prior for (3 that was elicited by Flournoy (1994) for estimating optimal treatment levels in a phase I clinical trial. ..."