Medical Definition of Senile plaque

1. Characteristic feature of the brains of Alzheimer's patients and aged monkeys, consisting of a core of amyloid fibrils surrounded by dystrophic neurites. The principal component of amyloid fibrils in senile plaques is B/A4, a peptide of about 4 kD that is derived from the larger amyloid precursor protein (APP). The B/A4 sequence is located near the C terminus of APP. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

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Lexicographical Neighbors of Senile Plaque

senile emphysema
senile fibroma
senile gangrene
senile haemangioma
senile halo
senile hip disease
senile involution
senile keratoderma
senile keratoma
senile keratosis
senile lenticular myopia
senile lentigo
senile memory
senile osteomalacia
senile plaque (current term)
senile plaques
senile psychosis
senile retinoschisis
senile sebaceous hyperplasia
senile tremor
senile wart

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